Multichannel system for on-line detection and control of the growth of bacterial biofilms using piezoelectric sensors
Bacterial microorganisms have an enormous capacity to join the surfaces of diverse materials (plastic, metal, ceramics) and develop complex biofilm-like structures (biofilms). When these structures are developed in medical implants, they can generate infections with serious repercussions for patients. Therefore, it is of interest to have systems that allow to monitor the growth of these biofilms in order to contribute to the performance of clinical trials to improve medical treatments.
Currently, there are no devices that allow testing multiple samples in parallel using techniques that allow non-destructive and continuous measurements. For this reason, this project aims to develop an analytical technique and a multichannel system for the on-line detection and control of the growth of bacterial biofilms, based on the use of piezoelectric sensors of the quartz resonator type (QCM).
The project includes the selection and design of the most suitable sensor package, the implementation of the entire electronic measurement system (in a way that is affordable and easy to use for non-expert users), the development of the software necessary for its operation , the validation of the necessary algorithms for the reliability of the measurements and the calibration and validation of the analytical technique.
Dr. Jorge Salazar Soler, Dr. Juan Antonio Chávez Domínguez, Dr. Miguel Jesús García Hernández, Dr. Miquel Àngel Amer Boixareu, Dr. Antoni Turó Peroy